Development of Fractalkine-Targeted Nanofibers that Localize to Sites of Arterial Injury

Atherosclerosis is the leading cause of death and disability around the world, with current treatments limited by neointimal hyperplasia. Our goal was to synthesize, characterize, and evaluate an injectable, targeted nanomaterial that will specifically bind to the site of arterial injury. Our target...

Full description

Bibliographic Details
Main Authors: Hussein A. Kassam, David C. Gillis, Brooke R. Dandurand, Mark R. Karver, Nick D. Tsihlis, Samuel I. Stupp, Melina R. Kibbe
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/10/3/420