Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum

Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum

Abstract Background According to the traditional tuberculosis (TB) treatment paradigm, the initial doses of treatment rapidly kill most Mycobacterium tuberculosis (Mtb) bacilli in sputum, yet many more months of daily treatment are required to eliminate a small, residual subpopulation of drug-tolera...

Full description

Bibliographic Details
Main Authors: Nicholas D. Walter, Camille M. Moore, Xavier A. Kayigire, Christian Dide-Agossou, William Worodria, Laurence Huang, Charles K. Everett, Gary S. Schoolnik, Payam Nahid, J. Lucian Davis
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
Mycobacterium tuberculosis
Treatment
Sputum
Drug tolerance
Differentially culturable
Online Access:http://link.springer.com/article/10.1186/s12879-018-3213-7

Internet

http://link.springer.com/article/10.1186/s12879-018-3213-7

Similar Items