Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells

<p>Abstract</p> <p>Background</p> <p>Spinocerebellar ataxia (SCA) refers to a disease entity in which polyglutamine aggregates are over-produced in Purkinje cells (PCs) of the cerebellum as well as other neurons in the central nervous system, and the formation of intrac...

Full description

Bibliographic Details
Main Authors: Ma Wei-Hsien, Chen Yu-Fan, Chiang Yi-Hung, Chen Ming-Hsiang, Chang You-Kang, Tseng Chian-You, Soong Bin-Wen, Ho Jennifer H, Lee Oscar K
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/18/1/54