Serine prevents LPS-induced intestinal inflammation and barrier damage via p53-dependent glutathione synthesis and AMPK activation

The role of serine in metabolic processes has recently attracted much attention as it could be used for the biosynthesis of purine, sphingolipids, and glutathione. The present study was conducted to investigate the effects of serine on LPS-induced intestinal inflammation and barrier dysfunction. The...

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Bibliographic Details
Main Authors: Xihong Zhou, Yumei Zhang, Liuqin He, Dan Wan, Gang Liu, Xin Wu, Yulong Yin
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617306345