ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?

Recently, the SARS-CoV-2 induced disease COVID-19 has spread all over the world. Nearly 20% of the patients have severe or critical conditions. SARS-CoV-2 exploits ACE2 for host cell entry. ACE2 plays an essential role in the renin–angiotensin–aldosterone system (RAAS), which regulates blood pressur...

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Bibliographic Details
Main Authors: Li Xiao, Hiroshi Sakagami, Nobuhiko Miwa
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/5/491