Chebulic acid inhibits advanced glycation end products-mediated vascular dysfunction by suppressing ROS via the ERK/Nrf2 pathway

Chebulic acid inhibits advanced glycation end products-mediated vascular dysfunction by suppressing ROS via the ERK/Nrf2 pathway

Advanced glycation end-products (AGEs) considered as a fatal mediator in the diabetic atherosclerotic pathology. In this study, we evaluated the effects of chebulic acid (CA) on anti-oxidant activities and its glycoaldehyde-induced AGEs (glycol-AGEs)-mediates systemic vascular dysfunction in endothe...

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Bibliographic Details
Main Authors: Mi-Hyun Nam, Won-rak Son, Sung-Yong Yang, Young-Seok Lee, Kwang-Won Lee
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Functional Foods
Subjects:
Advanced glycation end products
Oxidative stress
Nuclear factor E2-related factor
Inflammation
Vascular dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617303754

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http://www.sciencedirect.com/science/article/pii/S1756464617303754

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