Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms

Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms

Current schistosomiasis control strategies are largely based on chemotherapeutic agents and a limited number of drugs are available today. Praziquantel (PZQ) is the only drug currently used in schistosomiasis control programs. Unfortunately, this drug shows poor efficacy in patients during the earli...

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Bibliographic Details
Main Authors: Vanessa Silva-Moraes, Flávia Fernanda Bubula Couto, Marah Mileib Vasconcelos, Neusa Araújo, Paulo Marcos Zech Coelho, Naftale Katz, Rafaella Fortini Queiroz Grenfell
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2013-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Schistosoma mansoni
antischistosomal drugs
calcium channels antagonists
L-type calcium channels
nifedipine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000500600&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000500600&lng=en&tlng=en

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