Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury

Systemic metabolic reprogramming induced by infection exerts profound, pathogen-specific effects on infection outcome. Here, we detail the host immune and metabolic response during sickness and recovery in a mouse model of malaria. We describe extensive alterations in metabolism during acute infecti...

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Bibliographic Details
Main Authors: Michelle M Lissner, Katherine Cumnock, Nicole M Davis, José G Vilches-Moure, Priyanka Basak, Daniel J Navarrete, Jessica A Allen, David Schneider
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60165