Protective effects of silymarin on methotrexate-induced damages in rat testes
Abstract The present study aimed to investigate the protective effects of silymarin (SMN), an antioxidant, on methotrexate (MTX)-induced damage in rat testes. Thirty-two Wistar albino rats were divided into four groups (n = 8): control, MTX (20 mg/kg, i.p. on days 1 and 5), SMN (200 mg/kg, orally),...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2018-06-01
|
Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100618&lng=en&tlng=en |