Grape seed flavanols decrease blood pressure via Sirt-1 and confer a vasoprotective pattern in rats
Involvement of nitric oxide (NO) in the antihypertensive effect of grape seed flavanols was previously demonstrated. This study investigates the endothelial vasoprotective pattern and the role of Sirtuin-1 (Sirt-1) in this antihypertensive effect. Cafeteria diet-fed hypertensive rats (CHR) were admi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-06-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464616300512 |