Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.

Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.

Autophagy is a major degradative process responsible for the disposal of cytoplasmic proteins and dysfunctional organelles via the lysosomal pathway. During the autophagic process, cells form double-membraned vesicles called autophagosomes that sequester disposable materials in the cytoplasm and fin...

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Main Authors: Yeon Ja Choi, Yun Jung Park, Ji Young Park, Hyoung Oh Jeong, Dae Hyun Kim, Young Mi Ha, Ji Min Kim, Yu Min Song, Hyoung-Sam Heo, Byung Pal Yu, Pusoon Chun, Hyung Ryong Moon, Hae Young Chung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425474?pdf=render

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http://europepmc.org/articles/PMC3425474?pdf=render

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