Differential modulation of nitric oxide synthases in aging: therapeutic opportunities

Vascular aging is the term that describes the structural and functional disturbances of the vasculature with advancing aging. The molecular mechanisms of aging-associated endothelial dysfunction are complex, but reduced nitric oxide (NO) bioavailability and altered vascular expression and activity o...

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Bibliographic Details
Main Authors: Stêfany Bruno De Assis Cau, Fernando S Carneiro, Rita eTostes
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00218/full