Amnion-Derived Mesenchymal Stromal/Stem Cell Paracrine Signals Potentiate Human Liver Organoid Differentiation: Translational Implications for Liver Regeneration

Amnion-Derived Mesenchymal Stromal/Stem Cell Paracrine Signals Potentiate Human Liver Organoid Differentiation: Translational Implications for Liver Regeneration

The prevalence of end-stage liver diseases has reached very high levels globally. The election treatment for affected patients is orthotopic liver transplantation, which is a very complex procedure, and due to the limited number of suitable organ donors, considerable research is being done on altern...

Full description

Bibliographic Details
Main Authors: Antonio Lo Nigro, Alessia Gallo, Matteo Bulati, Giampiero Vitale, Diego Sebastian Paini, Mariangela Pampalone, Daniele Galvagno, Pier Giulio Conaldi, Vitale Miceli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Medicine
Subjects:
3D liver organoid culture
hepatocyte culture
human amnion-derived mesenchymal stem cells
liver regeneration
hepatic progenitor cell differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.746298/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.746298/full

Similar Items