Connectivity-based segmentation of the striatum in Huntington's disease: Vulnerability of motor pathways

The striatum, the primary site of degeneration in Huntington's disease (HD), connects to the cerebral cortex via topographically organized circuits subserving unique motor, associative and limbic functions. Currently, it is not known whether all cortico-striatal circuits are equally affected in...

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Bibliographic Details
Main Authors: India Bohanna, Nellie Georgiou-Karistianis, Gary F. Egan
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000647