The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?

The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?

Abstract The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the obse...

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Main Authors: Marc L. Molendijk, Eiko I. Fried, Willem Van der Does
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medicine
Online Access:http://link.springer.com/article/10.1186/s12916-018-1221-5
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spelling doaj-0c9ec550b9924d84b2eaa824e18bec992020-11-25T02:54:17ZengBMCBMC Medicine1741-70152018-12-011611310.1186/s12916-018-1221-5The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?Marc L. Molendijk0Eiko I. Fried1Willem Van der Does2Institute of Psychology, Clinical Psychology Unit, Leiden UniversityInstitute of Psychology, Clinical Psychology Unit, Leiden UniversityInstitute of Psychology, Clinical Psychology Unit, Leiden UniversityAbstract The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effect.http://link.springer.com/article/10.1186/s12916-018-1221-5
collection DOAJ
language English
format Article
sources DOAJ
author Marc L. Molendijk
Eiko I. Fried
Willem Van der Does
spellingShingle Marc L. Molendijk
Eiko I. Fried
Willem Van der Does
The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
BMC Medicine
author_facet Marc L. Molendijk
Eiko I. Fried
Willem Van der Does
author_sort Marc L. Molendijk
title The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_short The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_full The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_fullStr The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_full_unstemmed The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_sort smiles trial: do undisclosed recruitment practices explain the remarkably large effect?
publisher BMC
series BMC Medicine
issn 1741-7015
publishDate 2018-12-01
description Abstract The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effect.
url http://link.springer.com/article/10.1186/s12916-018-1221-5
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AT marclmolendijk smilestrialdoundisclosedrecruitmentpracticesexplaintheremarkablylargeeffect
AT eikoifried smilestrialdoundisclosedrecruitmentpracticesexplaintheremarkablylargeeffect
AT willemvanderdoes smilestrialdoundisclosedrecruitmentpracticesexplaintheremarkablylargeeffect
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