The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?

Abstract The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the obse...

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Bibliographic Details
Main Authors: Marc L. Molendijk, Eiko I. Fried, Willem Van der Does
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medicine
Online Access:http://link.springer.com/article/10.1186/s12916-018-1221-5