Puerarin alleviates streptozotocin (STZ)-induced osteoporosis in rats through suppressing inflammation and apoptosis via HDAC1/HDAC3 signaling

Puerarin alleviates streptozotocin (STZ)-induced osteoporosis in rats through suppressing inflammation and apoptosis via HDAC1/HDAC3 signaling

Diabetic osteoporosis is a severe public health concern in the world. Puerarin (PU) is extensively attractive due to its superior bioactivities. In the study, we found that PU protected against streptozotocin (STZ)-induced osteoporotic changes in rats. PU treatment improved STZ-induced diabetes in r...

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Bibliographic Details
Main Authors: Chang-Jun Guo, Jing-Jing Xie, Rong-Hua Hong, Han-Song Pan, Fu-Guo Zhang, Yi-Min Liang
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diabetic osteoporosis
Puerarin (PU)
Inflammation
Apoptosis
HDAC1/HDAC3
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218339805

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http://www.sciencedirect.com/science/article/pii/S0753332218339805

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