Inhibition of Radiation and Temozolomide-Induced Glioblastoma Invadopodia Activity Using Ion Channel Drugs

Inhibition of Radiation and Temozolomide-Induced Glioblastoma Invadopodia Activity Using Ion Channel Drugs

Glioblastoma (GBM) is the most prevalent and malignant type of primary brain cancer. The rapid invasion and dissemination of tumor cells into the surrounding normal brain is a major driver of tumor recurrence, and long-term survival of GBM patients is extremely rare. Actin-rich cell membrane protrus...

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Bibliographic Details
Main Authors: Marija Dinevska, Natalia Gazibegovic, Andrew P. Morokoff, Andrew H. Kaye, Katharine J. Drummond, Theo Mantamadiotis, Stanley S. Stylli
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
glioma
glioblastoma
invasion
invadopodia
ion channels
drug repurposing
Online Access:https://www.mdpi.com/2072-6694/12/10/2888

Internet

https://www.mdpi.com/2072-6694/12/10/2888

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