Overexpression of Heme Oxygenase-1 Prevents Renal Interstitial Inflammation and Fibrosis Induced by Unilateral Ureter Obstruction.

Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases. Many studies have demonstrated that heme oxygenase-1 (HO-1) is involved in diverse biological processes as a cytoprotective molecule, including anti-inflammatory, anti-oxidant, anti-apoptotic, antiprolife...

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Main Authors: Xiao Chen, Shi-Yao Wei, Jian-Si Li, Qing-Fang Zhang, Yu-Xiao Wang, Shi-Lei Zhao, Jing Yu, Chang Wang, Ying Qin, Qiu-Ju Wei, Gui-Xiang Lv, Bing Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4713170?pdf=render