Dengue Virus Serotype 2 and Its Non-Structural Proteins 2A and 2B Activate NLRP3 Inflammasome

Dengue Virus Serotype 2 and Its Non-Structural Proteins 2A and 2B Activate NLRP3 Inflammasome

Dengue is the most prevalent and rapidly transmitted mosquito-borne viral disease of humans. One of the fundamental innate immune responses to viral infections includes the processing and release of pro-inflammatory cytokines such as interleukin (IL-1β and IL-18) through the activation of inflammaso...

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Bibliographic Details
Main Authors: Gaurav Shrivastava, Giovani Visoso-Carvajal, Julio Garcia-Cordero, Moisés Leon-Juarez, Bibiana Chavez-Munguia, Tomas Lopez, Porfirio Nava, Nicolás Villegas-Sepulveda, Leticia Cedillo-Barron
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
dengue
inflammasome
non-structural proteins NS2A and NS2B
viroporins
IL-1β
NLRP3
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00352/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00352/full

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