Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells

<p>Abstract</p> <p>Background</p> <p>Cellular FLICE-Inhibitory Protein (long form, c-FLIP<sub>L</sub>) is a critical negative regulator of death receptor-mediated apoptosis. Overexpression of c-FLIP<sub>L</sub> has been reported in many cancer ce...

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Bibliographic Details
Main Authors: Wang Qilin, Sun Wendong, Hao Xuexi, Li Tianliang, Su Ling, Liu Xiangguo
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Cancer Cell International
Subjects:
Online Access:http://www.cancerci.com/content/12/1/54