Trajectory-based differential expression analysis for single-cell sequencing data
Downstream of trajectory inference for cell lineages based on scRNA-seq data, differential expression analysis yields insight into biological processes. Here, Van den Berge et al. develop tradeSeq, a framework for the inference of within and between-lineage differential expression, based on negative...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14766-3 |