AT1-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers

AT1-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers

Abstract Background Blockers of angiotensin II type 1 receptor (AT1R) and the voltage gated calcium channel 1.2 (CaV1.2) are commonly used for treatment of hypertension. Yet there is little information about the effect of physiological concentrations of angiotensin II (AngII) on AT1R signaling and w...

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Bibliographic Details
Main Authors: Kristoffer Bernhem, Kalaiselvan Krishnan, Alexander Bondar, Hjalmar Brismar, Anita Aperia, Lena Scott
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Calcium
AT1R
Cell imaging
VGCC
hypertension
Online Access:http://link.springer.com/article/10.1186/s12872-017-0562-x

Internet

http://link.springer.com/article/10.1186/s12872-017-0562-x

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