Protective Effect of Vitamin C on Triptolide-induced Acute Hepatotoxicity in Mice through mitigation of oxidative stress
Abstract: Triptolide, a purified diterpenoid from the herb Tripterygium wilfordii Hook.f., was widely used to treat many diseases. However, the hepatotoxicity of triptolide limited its clinical use. Research showed oxidative stress played an important role in triptolide-induced liver injury. To inve...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Ciências
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Series: | Anais da Academia Brasileira de Ciências |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300713&lng=en&tlng=en |