Estradiol upregulates calcineurin expression via overexpression of estrogen receptor alpha gene in systemic lupus erythematosus

Estradiol upregulates calcineurin expression via overexpression of estrogen receptor alpha gene in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease primarily affecting women (9:1 compared with men). To investigate the influence of female sex hormone estrogen on the development of female-biased lupus, we compared the expression of estrogen receptor alpha (ERα) gene and protein levels as...

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Bibliographic Details
Main Authors: Hui-Li Lin, Jeng-Hsien Yen, Shi-Shin Chiou, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Hong-Wen Liu, 林慧麗, 顏正賢, 邱世欣, 蔡文展, 歐燦騰, 吳正欽, 劉宏文
Format: Article
Language:English
Published: Wiley 2011-04-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Calcineurin
Estrogen
Estrogen receptor alpha gene
Systemic lupus erythematosus
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X10000409

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http://www.sciencedirect.com/science/article/pii/S1607551X10000409

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