Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma

Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma

Bone marrow mesenchymal stem/stromal cells (BMSCs) can be transformed into tumor-associated MSCs (TA-MSCs) within the tumor microenvironment to facilitate tumor progression. However, the underline mechanism and potential therapeutic strategy remain unclear. Here, we explored that interleukin 17 (IL-...

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Bibliographic Details
Main Authors: Qi Lou, Minyi Zhao, Quanhui Xu, Siyu Xie, Yingying Liang, Jian Chen, Lisha Yuan, Lingling Wang, Linjia Jiang, Lisha Mou, Dongjun Lin, Meng Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MSC
tumor associated MSC
retinoic acid
interleukin-17
interferon-γ
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.658757/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.658757/full

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