Retrovirally Transferred Genes Inhibit Apoptosis in an Insulin-Secreting Cell Line: Implications for Islet Transplantation
The transplantation of pancreatic islets for the treatment of type I diabetes is hindered by the enormous loss of cells due to early apoptotic events. Genetic engineering of islets with cytoprotective genes is an important strategy aimed to enhance the survival of these cells in the transplant setti...
Main Authors: | Elizabeth S. Fenjves, M. Sofia Ochoa, Carlota Gay-Rabinstein, Camillo Ricordi, Michael A. Curran |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2004-07-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/000000004783983710 |
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