Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer

Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community. Since the 1880s, laboratory diagnosis of tuberculosis has relied primarily on mic...

Full description

Bibliographic Details
Main Authors: Emma L. Doughty, Martin J. Sergeant, Ifedayo Adetifa, Martin Antonio, Mark J. Pallen
Format: Article
Language:English
Published: PeerJ Inc. 2014-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/585.pdf