The Role of Sirtuin-1 in the Vasculature: Focus on Aortic Aneurysm

Sirtuin-1 (SirT1) is a nicotinamide adenine dinucleotide-dependent deacetylase and the best characterized member of the sirtuins family in mammalians. Sirtuin-1 shuttles between the cytoplasm and the nucleus, where it deacetylates histones and non-histone proteins involved in a plethora of cellular...

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Bibliographic Details
Main Authors: Enkhjargal Budbazar, Francisca Rodriguez, José M. Sanchez, Francesca Seta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.01047/full