Peptide Phage Display as a Tool for Drug Discovery: Targeting Membrane Receptors

Ligands selected from phage-displayed random peptide libraries tend to be directed to biologically relevant sites on the surface of the target protein. Consequently, peptides derived from library screenings often modulate the target protein’s activity in vitro and in vivo and can be used as lead com...

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Bibliographic Details
Main Authors: Tomaz Bratkovic, Borut Strukelj, Peter Molek
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/1/857/