Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation

Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation

Background/Aims: Tonsillectomy may be an important method to achieve a long-term remission of IgAN, but patients’ physical status may limit their access to this surgery. We proposed an encouraging solution through inhibiting GADD34 expression in order to promote tonsillar mononuclear cells (TMCs) ap...

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Bibliographic Details
Main Authors: Xiaofei Peng, Tao Yang, Liyu He, Xian Chen, Yafeng Jiang, Hao Zhang, Hong Liu, Youming Peng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
IgA nephropathy
Tonsillar mononuclear cell
ER stress
GADD34
Cell apoptosis
Online Access:https://www.karger.com/Article/FullText/495061

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https://www.karger.com/Article/FullText/495061

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