Doxorubicin-loaded zein in situ gel for interstitial chemotherapy of colorectal cancer

Doxorubicin-loaded zein in situ gel for interstitial chemotherapy of colorectal cancer

The aim of this research was to evaluate doxorubicin (DOX)-loaded zein in situ gels, a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection. In vitro release of DOX-loaded zein was investigated and the pharmacokinetics, biodistribution...

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Bibliographic Details
Main Authors: Ning Shen, Jie Hu, Linan Zhang, Li Zhang, Yongjun Sun, Yinghua Xie, Shaomei Wu, Lei Liu, Zibin Gao
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Doxorubicin
Zein
In situ gel
Tumor
Intratumoral injection
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512001396

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http://www.sciencedirect.com/science/article/pii/S2211383512001396

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