Decreased STAT3 Phosphorylation Mediates Cell Swelling in Ammonia-Treated Astrocyte Cultures
Brain edema, due largely to astrocyte swelling, and the subsequent increase in intracranial pressure and brain herniation, are major complications of acute liver failure (ALF). Elevated level of brain ammonia has been strongly implicated in the development of astrocyte swelling associated with ALF....
Main Authors: | Arumugam R. Jayakumar, Kevin M. Curtis, Kiran S. Panickar, Nagarajarao Shamaladevi, Michael D. Norenberg |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-12-01
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Series: | Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-7737/5/4/48 |
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