Rescuing axons from degeneration does not affect retinal ganglion cell death

After a traumatic injury to the central nervous system, the distal stumps of axons undergo Wallerian degeneration (WD), an event that comprises cytoskeleton and myelin breakdown, astrocytic gliosis, and overexpression of proteins that inhibit axonal regrowth. By contrast, injured neuronal cell bodie...

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Bibliographic Details
Main Authors: S. de Lima, B.S. Mietto, C. Paula, T. Muniz, A.M.B. Martinez, P.F. Gardino
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2016-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000400705&lng=en&tlng=en