Hepatic bile acid uptake: effect of conjugation, hydroxyl and keto groups, and albumin binding
Hepatic extraction of trihydroxy (free, glyco- and tauro-conjugated) dihydroxy, and monohydroxy bile acids has been evaluated in single pass liver perfusion experiments in rats. The percentage of each bile acid bound to albumin was also evaluated by equilibrium dialysis. Conjugation increased bile a...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1982-11-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520380548 |