Embracing Metagenomic Complexity with a Genome-Free Approach

ABSTRACT A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (non-branching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have non-branching genomes. Tremendous discoveries i...

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Bibliographic Details
Main Authors: Izaak Coleman, Tal Korem
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00816-21