Embracing Metagenomic Complexity with a Genome-Free Approach
ABSTRACT A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (non-branching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have non-branching genomes. Tremendous discoveries i...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2021-08-01
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Series: | mSystems |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mSystems.00816-21 |