The PICALM protein plays a key role in iron homeostasis and cell proliferation.

The ubiquitously expressed phosphatidylinositol binding clathrin assembly (PICALM) protein associates with the plasma membrane, binds clathrin, and plays a role in clathrin-mediated endocytosis. Alterations of the human PICALM gene are present in aggressive hematopoietic malignancies, and genome-wid...

Full description

Bibliographic Details
Main Authors: Paula B Scotland, Jessica L Heath, Amanda E Conway, Natasha B Porter, Michael B Armstrong, Jennifer A Walker, Mitchell L Klebig, Catherine P Lavau, Daniel S Wechsler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3431333?pdf=render