Human stefin B role in cell's response to misfolded proteins and autophagy.

Alternative functions, apart from cathepsins inhibition, are being discovered for stefin B. Here, we investigate its role in vesicular trafficking and autophagy. Astrocytes isolated from stefin B knock-out (KO) mice exhibited an increased level of protein aggregates scattered throughout the cytoplas...

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Bibliographic Details
Main Authors: Mira Polajnar, Tina Zavašnik-Bergant, Katja Škerget, Matej Vizovišek, Robert Vidmar, Marko Fonović, Nataša Kopitar-Jerala, Uroš Petrovič, Susanna Navarro, Salvador Ventura, Eva Žerovnik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105463?pdf=render