Cytoprotective Effects of Dinitrosyl Iron Complexes on Viability of Human Fibroblasts and Cardiomyocytes

Cytoprotective Effects of Dinitrosyl Iron Complexes on Viability of Human Fibroblasts and Cardiomyocytes

Nitric oxide (NO) is an important signaling molecule that plays a key role in maintaining vascular homeostasis. Dinitrosyl iron complexes (DNICs) generating NO are widely used to treat cardiovascular diseases. However, the involvement of DNICs in the metabolic processes of the cell, their protective...

Full description

Bibliographic Details
Main Authors: Natalia Pavlovna Akentieva, Natalia Alekseevna Sanina, Artur Rasimovich Gizatullin, Natalia Ivanovna Shkondina, Tatyana Romanovna Prikhodchenko, Stanislav Ivanovich Shram, Nikolai Zhelev, Sergei Michailovich Aldoshin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
dinitrosyl iron complexes
donors nitric oxide
heart disease
cell viability
membrane potential
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01277/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01277/full

Similar Items