Echinacoside Inhibits Glutamate Release by Suppressing Voltage-Dependent Ca2+ Entry and Protein Kinase C in Rat Cerebrocortical Nerve Terminals

Echinacoside Inhibits Glutamate Release by Suppressing Voltage-Dependent Ca2+ Entry and Protein Kinase C in Rat Cerebrocortical Nerve Terminals

The glutamatergic system may be involved in the effects of neuroprotectant therapies. Echinacoside, a phenylethanoid glycoside extracted from the medicinal Chinese herb Herba Cistanche, has neuroprotective effects. This study investigated the effects of echinacoside on 4-aminopyridine-evoked glutama...

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Bibliographic Details
Main Authors: Cheng Wei Lu, Tzu Yu Lin, Shu Kuei Huang, Su Jane Wang
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
echinacoside
glutamate release
cerebrocortical nerve terminals
voltage-dependent Ca2+ channels
protein kinase C
Online Access:http://www.mdpi.com/1422-0067/17/7/1006

Internet

http://www.mdpi.com/1422-0067/17/7/1006

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