Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development

Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development

The maintenance of physiological levels of nitric oxide (NO) produced by eNOS represents a key element for vascular endothelial homeostasis. On the other hand, NO overproduction, due to the activation of iNOS under different stress conditions, leads to endothelial dysfunction and, in the late stages...

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Bibliographic Details
Main Authors: Micaela Gliozzi, Miriam Scicchitano, Francesca Bosco, Vincenzo Musolino, Cristina Carresi, Federica Scarano, Jessica Maiuolo, Saverio Nucera, Alessia Maretta, Sara Paone, Rocco Mollace, Stefano Ruga, Maria Caterina Zito, Roberta Macrì, Francesca Oppedisano, Ernesto Palma, Daniela Salvemini, Carolina Muscoli, Vincenzo Mollace
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
oxidized LDLs
constitutive NO synthase cNOS
inducible NO synthase (iNOS)
endothelial dysfunction
Online Access:https://www.mdpi.com/1422-0067/20/13/3294

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https://www.mdpi.com/1422-0067/20/13/3294

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