Simultaneous determination of borneol and its metabolite in rat plasma by GCâMS and its application to pharmacokinetic study

A gas chromatography mass spectrometry (GCâMS) method has been developed and fully validated for the simultaneous determination of natural borneol (NB) and its metabolite, camphor, in rat plasma. Following a single liquidâliquid extraction, the analytes were separated using an HP-5MS capillary colum...

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Bibliographic Details
Main Authors: Xiu-Man Sun, Qiong-Feng Liao, Yu-Ting Zhou, Xue-Jiao Deng, Zhi-Yong Xie
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177914000069