TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
<p>Abstract</p> <p>The role of tumor necrosis factor (TNF) as an immune mediator has long been appreciated but its function in the brain is still unclear. TNF receptor 1 (TNFR1) is expressed in most cell types, and can be activated by binding of either soluble TNF (solTNF) or trans...
Main Authors: | Tansey Malú G, McCoy Melissa K |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/5/1/45 |
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