A Novel Single Domain Antibody Targeting FliC Flagellin of Salmonella enterica for Effective Inhibition of Host Cell Invasion

A Novel Single Domain Antibody Targeting FliC Flagellin of Salmonella enterica for Effective Inhibition of Host Cell Invasion

The enteric pathogen, Salmonella enterica is a major cause of human gastroenteritis globally and with increasing bacterial resistance to antibiotics, alternative solutions are urgently needed. Single domain antibodies (sdAbs), the smallest antibody fragments that retain antigen binding specificity a...

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Bibliographic Details
Main Authors: Jennifer Huen, Zhun Yan, Jeremy Iwashkiw, Shraddha Dubey, Maria C. Gimenez, Maria E. Ortiz, Saumil V. Patel, Michael D. Jones, Ali Riazi, Mauricio Terebiznik, Saeid Babaei, Dea Shahinas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
single domain antibody
Salmonella enterica
pathogen
bacterial motility
bacterial invasion
binding affinity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02665/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02665/full

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