Aspirin mediates histone methylation that inhibits inflammation-related stemness gene expression to diminish cancer stemness via COX-independent manner

Aspirin mediates histone methylation that inhibits inflammation-related stemness gene expression to diminish cancer stemness via COX-independent manner

Abstract Background The widely recognized anti-cancer potential of aspirin has created a broad interest to explore the clinical benefits of aspirin in cancer therapy. However, the current understanding of the molecular mechanisms involved in the anti-cancer potential of aspirin remains limited. Meth...

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Bibliographic Details
Main Authors: Xiaoyuan Zhang, Renle Du, Na Luo, Rong Xiang, Wenzhi Shen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Aspirin
Histone methylation
Cancer stemness
ICAM3
COX
Therapeutic strategies
Online Access:http://link.springer.com/article/10.1186/s13287-020-01884-4

Internet

http://link.springer.com/article/10.1186/s13287-020-01884-4

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