From Experiments to Simulation: Shear-Induced Responses of Red Blood Cells to Different Oxygen Saturation Levels

Red blood cells (RBC) carry and deliver oxygen (O2) to peripheral tissues through different microcirculatory regions where they are exposed to various levels of shear stress (SS). O2 affinity of hemoglobin (Hb) decreases as the blood enters the microcirculation. This phenomenon determines Hb interac...

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Bibliographic Details
Main Authors: Elif Ugurel, Senol Piskin, Ali Cenk Aksu, Aysenur Eser, Ozlem Yalcin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01559/full