A robust statistical method for association-based eQTL analysis.

It has been well established that theoretical kernel for recently surging genome-wide association study (GWAS) is statistical inference of linkage disequilibrium (LD) between a tested genetic marker and a putative locus affecting a disease trait. However, LD analysis is vulnerable to several confoun...

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Bibliographic Details
Main Authors: Ning Jiang, Minghui Wang, Tianye Jia, Lin Wang, Lindsey Leach, Christine Hackett, David Marshall, Zewei Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3153488?pdf=render