Role of Kisspeptin and Neurokinin B in Puberty in Female Non-Human Primates

In human patients, loss-of-function mutations in the genes encoding kisspeptin (KISS1) and neurokinin B (NKB) and their receptors (KISS1R and NK3R, respectively) result in an abnormal timing of puberty or the absence of puberty. To understand the neuroendocrine mechanism of puberty, we investigated...

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Bibliographic Details
Main Authors: Ei Terasawa, James P. Garcia, Stephanie B. Seminara, Kim L. Keen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00148/full