Senescent vs. non-senescent cells in the human annulus in vivo: Cell harvest with laser capture microdissection and gene expression studies with microarray analysis

<p>Abstract</p> <p>Background</p> <p>Senescent cells are well-recognized in the aging/degenerating human disc. Senescent cells are viable, cannot divide, remain metabolically active and accumulate within the disc over time. Molecular analysis of senescent cells in tissu...

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Bibliographic Details
Main Authors: Ingram Jane A, Hoelscher Gretchen L, Gruber Helen E, Zinchenko Natalia, Hanley Edward N
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/10/5