Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity.

In order to generate hypotheses regarding the mechanisms by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin) causes toxicity, we analyzed global gene expression changes in developing zebrafish embryos exposed to this potent toxicant in the context of a dynamic gene network. For this purpose, we al...

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Bibliographic Details
Main Authors: Andrey Alexeyenko, Deena M Wassenberg, Edward K Lobenhofer, Jerry Yen, Elwood Linney, Erik L L Sonnhammer, Joel N Meyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2864754?pdf=render